6x1 – Two's Company
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6x2 – Cross My Heart
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6x3 – Safe and Sorry
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6x4 – Relative Values
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6x5 – High Anxiety
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6x6 – The Wish List
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6x7 – Sweet as a Lollipop
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6x8 – Last Chance
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6x9 – The Replacement
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6x10 – Past Caring
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6x11 – Having It All
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6x12 – Pardon
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6x13 – Say the Word
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6x14 – An Even Stranger Danger
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6x15 – A Piece of Paper
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6x16 – Primary Care
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6x17 – Don't Ask, Don't Tell
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6x18 – Gap Year
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6x19 – Misconceptions
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6x20 – Rotten Eggs
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6x21 – Sticks and Stones
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6x22 – A Lion or a Sheep
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6x23 – A Soft Touch
A ditsy, but sexy, new receptionist, Sarah Finch, starts at the Best Practice. She impresses Dr. Eliot though by helping to fix his car.
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6x24 – A Matter of Faith
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6x25 – Forget-Me-Not
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6x26 – Night People
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6x27 – My Way or the Highway
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6x28 – Too Darn Hot
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6x29 – Butterfingers
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6x30 – Monstrous Regiment
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6x31 – Rolling Stone
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6x32 – This Too Too Solid Flesh
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6x33 – Hasty Hearts
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6x34 – Daddy's Girl
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6x35 – Keeping Mum
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6x36 – Flower Power
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6x37 – Lost and Found
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6x38 – Hooked
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6x39 – Extreme
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6x40 – Off the Chest
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6x41 – A Game of Soldiers
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6x42 – Family Secrets
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6x43 – Moving On
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6x44 – Sweet Dreams
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6x45 – On the Ropes
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6x46 – Wild, Wild West Midlands
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6x47 – A Decisive Moment
Helen declares that she is not in love with Mark, so he leaves with Robert, very upset. Helen cries. Ronnie returns from Australia declaring that his marriage to George is over.
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6x48 – Promises, Promises
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6x49 – A Species of Happiness
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6x50 – Ill Feelings
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6x51 – Over the Fence
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6x52 – Catchy Monkey
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6x53 – Beat Surrender
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6x54 – The Games People Play
George returns to Letherbridge from the Outback. She sorts out her misunderstanding with Ronnie, and they hug happily.
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6x55 – Angel of Mercy
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6x56 – When Love Hurts
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6x57 – A Wing and a Prayer
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6x58 – A Secret Life
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6x59 – Love Thy Neighbour
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6x60 – Prince Charming
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6x61 – Living the High Life
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6x62 – Overdue
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6x63 – Dangerous Loads
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6x64 – Only Connect
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6x65 – Watching Myself Die
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6x66 – One Foot in the Grave
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6x67 – Complex Adonis
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6x68 – They Never Cut the Cord
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6x69 – In the House of the Dead
A new nurse, Tasha Verma, arrives at Riverside and proceeds to cause chaos with Nathan's hormones.
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6x70 – Love Lies Bleeding
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6x71 – Out of Control
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6x72 – What If
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6x73 – Life Skills
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6x74 – An Inspector Called
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6x75 – One for Sorrow
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6x76 – Party Games
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6x77 – Rabbit in the Headlights
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6x78 – The Way to a Man's Heart
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6x79 – Colour Blind
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6x80 – Greens and Blues
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6x81 – Practice Run
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6x82 – Letting Go
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6x83 – My Son the Dramatic
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6x84 – Uncertain Justice
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6x85 – Sleepover
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6x86 – A Friend in Need
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6x87 – Noughts and Crosses
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6x88 – Ugly Duckling
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6x89 – Perfect
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6x90 – Lest We Forget
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6x91 – Change of Heart
Chloe's date around Ben's apartment got off to a bad start when she accidentally set fire to it. The box of fireworks under the table didn't help things. Ben got trapped under lots of rubble, Chloe tore her fishnets.
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6x92 – Behind You
Ben ends up in hospital on life support, following the fire.
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6x93 – Always in My Heart
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6x94 – Wake Up Call
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6x95 – Born to Fly
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6x96 – A Day to Remember
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6x97 – Listen to Me
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6x98 – Doctor at Large
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6x99 – Heart Strings
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6x100 – One Last Request
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6x101 – Medicine Without Frontiers
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6x102 – Hemmed In
The doctors dress up as pop and film stars to make money for 'Children in Need'.
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6x103 – Ambulance Chasers
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6x104 – The Daughter I Never Had
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6x105 – A Wake of Vultures
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6x106 – Mother's Pride
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6x107 – A Walk in the Park
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6x108 – Passing By
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6x109 – Sharp Seedlings
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6x110 – What the Doctor Saw
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6x111 – Risky Business
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6x112 – A Season in Hell
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6x113 – Cuckoo in the Nest
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6x114 – Spotless
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6x115 – Intolerance
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6x116 – Damaged Roots
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6x117 – Missing
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6x118 – The Merry Widow
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6x119 – A Woman of No Importance
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6x120 – Old Wounds
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6x121 – What He Wanted
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6x122 – Golden Girl
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6x123 – Bringing Up Baby
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6x124 – Swansong
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6x125 – Dim Tresbasu
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6x126 – True Romance
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6x127 – Conflicts of Interest
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6x128 – Little Lies
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6x129 – Leap in the Dark
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6x130 – Beneath the Surface
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6x131 – Crowded House
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6x132 – Home Front
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6x133 – Dream Lover
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6x134 – Past Imperfect
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6x135 – Coming to Terms
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6x136 – The Happiest Day
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6x137 – Sky Burial
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6x138 – Intervention
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6x139 – Trophy Life
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6x140 – Old Habits
Mary Longworth, an elderly respectable woman, suddenly freaks out in a supermarket for no apparent reason, causing damage and getting herself arrested. It turns out that she has been on the same medication for many years but all of a sudden it has started to produce a bizarre side effect, explaining her uncharacteristic behaviour.
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6x141 – Real Gone Kid
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6x142 – No Place Like Home
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6x143 – Sleight of Hand
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6x144 – Into the Light
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6x145 – Sleepless Nights
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6x146 – Harsh Words
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6x147 – For Love
Jack's ex wife Ria turns up to try and mess up relations between him and Dr. Helen.
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6x148 – Flesh and Blood
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6x149 – Watched
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6x150 – Wedding Nerves
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6x151 – Death of a Mouse
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6x152 – Skinhead
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6x153 – The Road to Enlightenment
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6x154 – Lack of Conviction
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6x155 – A Good Mate?
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6x156 – The Sweet Silver Song of the Lark
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6x157 – Brothers
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6x158 – A Rose for Delilah
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6x159 – Lifepact
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6x160 – A Night to Remember
It's Sarah's birthday, and she and the girls drag a downbeat Helen out for a wild girl's night out. Helen gets really drunk, starts a fight, and gets arrested. Jack proposes to her.
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6x161 – Happy Families
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6x162 – Sport for All
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6x163 – Fat Chance
Helen says "yes" to Jack's marriage proposal.
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6x164 – The Hand That Rocks the Cradle
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6x165 – In the Library, with the Candlestick: Part 1
Helen, Jack, George and Ronnie go on a Murder Mystery Weekend at a country house. Lots of fun and frolics ensue.
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6x166 – In the Library, with the Candlestick: Part 2
The murder mystery weekend goes horribly wrong when somebody really gets attacked.
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6x167 – Is There a Doctor in the House?
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6x168 – Cause for Concern
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6x169 – Table for Two
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6x170 – All That Glitters
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6x171 – The Devil You Know
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6x172 – My Own Flesh and Blood
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6x173 – Boundaries
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6x174 – Feeling the Heat
A masked intruder sets fire to gas cylinders in the Riverside reception, setting off a massive explosion. Sarah gets caught in the blast, whilst Helen, Jack, (who have also just announced their engagement), Nathan and Tasha are all trapped inside.
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6x175 – Wino
The doctors try to rescue their friends in the aftermath of the explosion, and find out who was responsible.
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6x176 – Under a Bushel
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6x177 – No Go
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6x178 – Stags at Bay
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6x179 – Birthing Pains
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6x180 – Your Very Good Health
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6x181 – Skylarks
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6x182 – Doctor's Orders
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6x183 – Sons and Strangers
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6x184 – When Two Become One
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6x185 – Hard to Swallow
Julia gets arrested for causing the surgery explosion.
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6x186 – Lucky for Some
Jack and Ria get into an argument. She pushes him down the stairs, and then takes an overdose. Jack goes into shock and dies in Helen's arms. Julia gets locked up, and Nathan finally comes round after the explosion.
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