The midwives answer the call for medical help in the Outer Hebrides.

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In January 1965, a diphtheria outbreak sweeps through Poplar and Mother Mildred seeks to help a distraught woman who abandoned her newborn.

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Sister Julienne intervenes in the case of a pregnant prostitute, a family's plan to leave Poplar are up in the air when a mysterious illness strikes, and Sgt. Woolf faces a health crisis of his own.

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Lucille encounters a defiant expectant mother who is less than kind, Phyllis attempts to help an immigrant mother with an alarming medical condition, and Shelagh and Trixie put on a fashion show to raise funds for the maternity home.

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Nonnatus House welcomes four male junior doctors to live and work among the midwives while Fred tries to help a sick man whose home is to be demolished.

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The plight of a harried matriarch profoundly affects Sister Julienne and Sister Frances, while Sister Hilda helps a nervous expectant father.

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Valerie's cousin Maureen endures a difficult labor and subsequent issues, while the Turners' adoption of May comes under threat.

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Trixie helps a blind mother care for her new baby, Kevin makes an error which troubles Sister Frances, and Valerie becomes concerned for her grandmother.

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The local council threatens to cut funding to Nonnatus House, which may face demolition. Two pregnant women discover they have something surprising in common.

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