A man whose daughter disappeared years earlier disappears himself while searching for another lost child. Meanwhile, Jack is relegated to desk duty as the new boss comes in.

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A designer is kidnapped, and the woman's boss, father, and lover are all persons of interest. Meanwhile, Jack contemplates a job offer from the private sector.

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Jack helps look for a white-collar criminal who has escaped from prison and may be tied to a multi-million dollar bank heist

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A teenage boy's disappearance appears to be related to either his father's job busting counterfeiters for the government, or selling tests to classmates at his prep school.

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Agent Medina makes a controversial decision to take manpower away from a case involving a missing woman and move it to an Amber Alert case.

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A bank employee's disappearance is tied to $100,000 in stolen money and an unwanted pregnancy from the woman's past.

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While investigating the disappearance of a paraplegic man, the FBI discovers that an insurance fraud investigator was harassing him, and that he was involved with a group that busted sexual predators.

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Jack takes Samantha with him to Los Angeles to help investigate the disappearance of the COO of an airline charter business, but he also has an ulterior motive.

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A medical resident's disappearance is connected to two of her former foster brothers, who are in trouble with the mob.

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The disappearance of a mean spirited, self-centered weatherman who had recently tried to change his ways leads the FBI to a group of Civil War reenactors.

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A 13-year-old girl torn apart by her feuding parents over custody and visitation rights disappears hours after her mother kidnaps her.

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While the team investigates the disappearance of a struggling bar owner who recently discovered a "weeping" statue of St. Teresa, the biological father of Sam's son wants back into his life.

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Agent Delgado's former police partner goes missing after an undercover deal goes bad, but Delgado fails to inform Jack that she may have a connection to the real reason why she's missing.

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Two suburban wives are abducted by a mob enforcer. But which one is he after, and why?

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What appears to be the disappearance of a college student becomes more complicated when the team discovers that the victim is an impostor with multiple identities.

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A mother and infant son disappear, but it turns out to be a fake kidnapping to protect them from a dangerous man from the father's past. But it turns out that a dangerous man from the mother's past puts the plan in jeopardy.

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The team discovers that a missing trial consultant who helps profile prospective jurors was killed because he was investigating jury tampering in a mob trial.

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A missing psychologist may have found evidence that his brother, a convicted serial rapist, is innocent.

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While the team investigates the disappearance of a Russian immigrant who was trying to bring her "brother" into the United States, Samantha recovers in the hospital from her automobile accident.

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The CEO of a failing ski supply company disappears after his plane crashes in the Pennsylvania woods, and the team thinks it's connected to his millionaire father. Meanwhile, Martin gets new disturbing news about his girlfriend.

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A journalist investigating a politician disappears. The team discovers that she checked herself into a mental health facility, but is she checking a source or having a breakdown of her own?

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A young woman's kidnapping is accidentally recorded on a pirated DVD bought in Chinatown. The team discovers that it is connected to an ancient Chinese ritual that could result in the victim's death.

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Jack's daughter's boyfriend disappears soon after he moves from Chicago to New York to be with her. Samantha struggles with a complication in her home life, and Danny and Elena prepare for their wedding.

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A former diver disappears, and his girlfriend is kidnapped. Meanwhile, Jack's daughter wants to move back to Chicago, Sam must choose between Jack and Brian, and Danny and Elena plan to get married that evening.

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