Eddie surprises the boys with sudden wedding plans. Hank helps out an overworked senatorial candidate and finds a possible romantic interest. Jeremiah returns but struggles with his first patient. Divya faces a dilemma with medical school.

Evan could be in hot water after a hospital data breach. Jeremiah has an unexpected visit from his parents. Hank helps out a stuntwoman and has a much-anticipated first date. Boris turns to Hank for help with his son.

Hank finds romance in Hong Kong while preventing the theft of Boris's medical records. Divya treats a repo man bent on taking back a yacht. Paige convinces Evan to rethink their parenting path.

In the 100th episode, Hank works a shift in the ER for the first time in years. Jill makes a surprise visit to the Hamptons. Jeremiah bonds with a patient he secretly admires, and Divya worries for a patient.

A visit to his old mentor and a serious diagnosis for agent Ken Keller cause Hank to rethink his future. Evan struggles to be more supportive as Paige tries to get pregnant. Jeremiah tries to shoot a video for Divya's baby shower.

Hank meets a woman who fears she has an inherited disease. Eddie makes a medical decision without consulting Hank. Jeremiah learns that Boris went to clinical trials without his input.

Hank helps a theater legend as she deals with confusion and memory loss at Eddie's wedding. He also reconciles Eddie and Evan before the ceremony. Paige & Evan await pregnancy test results.

HankMed temporarily dissolves as each important player in the business is off to bigger and better things--except for Hank, who still has no idea what the future holds for him.