Sam and Quincy are attending a job fair for students when a woman falls down an escalator, just after shouting at someone who has been following her. While she is in hospital it is discovered she has a severe case of posttraumatic amnesia. A high price assassin is caught in her hospital room not long afterwards and leads to even more interest in who she is and why someone would want her dead.

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When a young girl dies in a car crash, Quincy's investigation leads him to some disquieting numbers about emergency room care and the need for trauma centers to handle the critically injured.

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Quincy and Janet finally get some time off and go on a weeks cruise. They are looking forward to some rest and relaxation together. Before long their holiday is interrupted. Quincy is visited, late one night, by the captain. One of his crew has been murdered and he would like Quincy's advice. The murderer is caught but he has died before the morning and an autopsy reveals that he could have died from an infectious disease. A disease that could already be spreading throughout the ship!

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With the cruise ship being prevented from docking at any of the islands in the area it is down to Quincy and Janet to find out exactly what the disease on board is before everyone on the ship finds out and starts panicking.

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Quincy gets involved in an anti drunk driving campaign after a tough case involving a pedestrian being killed by a prominent lawyer-with a surprising twist.

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Quincy investigates the death of a ranch owner while Dr. Astin and his wife struggle with their foster child.

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Quincy helps a cancer patient who is dying.

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A truck driver dies just days after being splashed by a caustic chemical he was illegally dumping. Quincy uncovers the cause of his death and investigates further, trying to find where the chemicals were dumped before it rains and a dangerous chemical cloud is created.

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When a high school student drops dead at basketball practice, Quincy is drawn into an investigation in the dangers of "pep" pills and legal lookalike drugs and the problems in regulating the sales of such items.

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When a series of murders committed by the same gun, but by different killers, crosses his table, Quincy goes on the hunt for the gun and investigates the problems surrounding hand gun ownership.

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Quincy investigates the death of a horse.

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When a fire at a hotel leaves twelve dead, Quincy goes on the hunt for an arsonist, leading him to discover an arson anonymous group, and a vanity fire starter.

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When a baby with Down syndrom's denied medical care after birth, the physician allows it starve to death, Quincy must determine if the death was from natural causes, or if the attending doctor had a different agenda.

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A young man diagnosed with schizophrenia brutally murders his father, brother and sister, then surrenders to the police. Quincy believes he may be faking his mental illness.

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Quincy goes on a campaign to clean up the Los Angeles air after an old man and a young boy die during an atmospheric inversion.

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After a former Vietnam nurse suffering from PTSD turns up dead, Quincy gets involved with a veteran support group in an effort to get the victim's friend, another former nurse, the treatment she needs for her disorder.

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A mistake at a hospital leads to a nurses strike which Quincy and Astin try to clear up.

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Quincy investigates the murder of an Auschwitz survivor. He also tries to help a friend fight a law suit claiming the Holocaust never happened.

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A woman, Vicki Maguire, who has suffered from agoraphobia, manages to finally leave her house, for the first time in seven years. While walking her dog along the beach beside her house she looks in through the window of another house, and witnesses what she thinks is a woman being strangled. The police are called and when Monahan and Brill get to the house there is no body, no sign of a struggle and a completely different man in residence. No one believes her story, except for her psychologist Dr. Rainer, and she goes to see Quincy. She persuades him that the woman wasn't seeing things and that he should help her find out the truth, before she suffers a relapse and will never be able to leave her house again.

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Quincy's reputation is called into question on the eve of the trial of mob boss in which Quincy is the star witness.

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After running into an ex-girlfriend he had a fall-out with years ago, Quincey finds himself on the case when her husband dies and must unweave a diabolical plot to reveal the killer's identity.

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After a microchip is found in an admiral's body, during an autopsy, Quincy is reinstated into the Navy to find a spy. Unfortunately for Quincy, the old Admiral had more than one secret to keep.

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While investigating the death of a child by the family's guard dog, Quincy adopts a dog of his own.

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A family goes through the grieving process, while Quincy investigates the death of their son, who was killed during a college hazing ritual.

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