12x1 – Episode 1
A horrific murder at the public introduction of the Murdochs' new residence designed by Frank Lloyd Wright puts the couple on the case.
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12x2 – Episode 2
A post-operative death of a patient of a surgery that Dr. Ogden participated in leads her to suspect murder in the hospital.
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12x3 – Episode 3
At the wedding of Henry Higgins and Ruth Newsome on the Newsome estate, random murder attempts on Higgens are just the beginning of the machinations happening there.
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12x4 – Episode 4
When a harsh new immigration law comes into force, the Murdochs and Inspector Brackenreid find themselves dealing with its fallout with its enforcers and the Greek immigrants targeted by it.
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12x5 – Episode 5
When a French diplomat to a secret international meeting to create the Triple Entente is found dead, Murdoch is drafted to temporarily impersonate him.
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12x6 – Episode 6
Murdoch investigates an astronomical phenomenon with a strange impact on his colleagues' behavior and dire implications for Toronto.
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12x7 – Episode 7
After a telephone call reports a body has been discovered, as well as reports of gunshots have been reported, Murdoch and Crabtree find an unlikely suspect cowering near the body. Murdoch suspects the true killer is still out there.
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12x8 – Episode 8
When a wealthy, high society couple is found drowned in their pool in an apparent double suicide, Murdoch suspects murder.
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12x9 – Episode 9
Inspector Brackenreid travels to St. Marys to help an old flame whose daughter is missing, and he happens to learn then that he is her father.
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12x10 – Episode 10
Murdoch helps a detective recover a ship loaded with antiques. Brackenreid considers leaving.
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12x11 – Episode 11
Crabtree and John are transporting a convicted axe murderer to prison when she escapes to exact revenge on those who testified against her.
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12x12 – Episode 12
Murdoch's distressing childhood memories are evoked while investigating the death of an orphan under the care of the same Jesuit priest who taught him.
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12x13 – Episode 13
Murdoch enlists inventor Nikola Tesla to help with the murder investigation of a man experimenting with invisibility.
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12x14 – Episode 14
When a man dies in a deliberately set fire, Murdoch's investigation reveals some shocking personal history.
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12x15 – Episode 15
When a man is electrocuted during a typing contest with Crabtree and Louise Cherry, Murdoch suspects the reporter was the intended target.
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12x16 – Episode 16
After the release of Murdoch and Ogden's book, a series of copycat murders begin to take place.
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12x17 – Episode 17
As Murdoch seeks a promotion, a constable is shot in a botched raid on an opium den led by Watts.
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12x18 – Episode 18
Murdoch suspects John is being framed for murder by Inspector McWorthy and Brackenreid goes after the corrupt copper.
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