1x1 – Episode 1
Dr. Sam Griffith takes over as the new chief of surgery after her renowned boss, Dr. Rob "Griff" Griffith, falls into a coma.
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1x2 – Episode 2
Dr. Griffith fights to keep her new leadership role as chief of surgery when her father takes his case for reinstatement to the hospital board. Dr. Caleb Tucker forms an unexpected connection to a patient battling a mystery condition.
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1x3 – Episode 3
When Dr. Sam Griffith (Sophia Bush) refuses to concede her role as chief, her father Griff orchestrates a costly surprise. Also, Sam's mother, hospital administrator Vivian, turns to her new spouse, therapist Asher Pyne, for help navigating the battle between her daughter and ex-husband.
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1x4 – Episode 4
When Dr. Sam Griffith tracks down a deep-pocketed anonymous hospital donor, she's shocked to discover why the donor is so loyal to her father, Griff. Also, Griff offers to mentor his daughter and assure her succession.
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1x5 – Episode 5
When a gunshot victim is rushed to the emergency room, the incident triggers flashbacks to the aftermath of Griff's own shooting.
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1x6 – Episode 6
Secrets revealed at a major fundraising gala for the hospital threaten to end a tenuous truce between Dr. Sam Griffith and her father. Cardiothoracic resident Dr. Lex Trulie makes a decision that could alter her career trajectory.
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1x7 – Episode 7
Dr. Griffith deals with the fallout following her actions at the hospital fundraising gala. Griff returns to the operating room for the first time since his shooting to perform a bypass surgery. Malcolm's estranged mother arrives in town.
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1x8 – Episode 8
When Amy Taylor (Bethany Joy Lenz) is admitted to the hospital accompanied by her sister, Gretchen (Hilarie Burton) , with signs of premature heart disease, Dr. Sam Griffith discovers a deeper medical mystery. Also, Griff anxiously awaits the results of his MRI, hoping to get to the root of his troubling symptoms.
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1x9 – Episode 9
A devastating storm leads to an overflow of patients and limited resources; Dr. Sam Griffith's team must make impossible choices about their patients' care. Also, Griff connects with a young patient admitted with a rare heart condition.
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1x10 – Episode 10
In the aftermath of a devastating storm, Dr. Sam Griffith and her father, Griff, come together to support her injured mother, Vivian. Also, Dr. Lex Trulie and Dr. Joey Costa each make pivotal decisions about their futures.
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1x11 – Episode 11
As Griff completes his proctorship and prepares to make his official return to surgery, hospital board chairwoman Tina Kingsley (Victoria Rowell) makes a stunning announcement that threatens the future of Lakeshore Sentinel. Also, Lex meets her no-nonsense new boss, and the conflict between Isan and Joey comes to a head as the surgical team prepares for a high-stakes lung transplant.
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1x12 – Episode 12
As Sam, Griff and Vivian face the fallout from Griff's bombshell confession to the hospital board, the surgical team preps for a rare high-profile surgery that could take Sam's career to the next level. Also, Lex confronts Griff about his betrayal, and Malcolm sets his sights on his mother's board seat.
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1x13 – Episode 13
The on-again/off-again battle between Dr. Sam Griffith (Sophia Bush) and Dr. Rob "Griff" Griffith (Jason Isaacs) is back on. The battle takes a shocking turn that will irrevocably change their family dynamic and the future of the hospital, in the Season 1 finale.
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