With both parents away, Drake turns their home into a bed and breakfast inn. Seventy-five college students later, a spring break party takes over the house.

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Megan competes against Drake and Josh in a salsa-making contest where a new Plasma Screen TV is the grand prize.

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Josh's long-time e-pal, Yooka, decides to visit from Yudonia, but a supposed Yudonian friendship ceremony makes Drake her husband.

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It's Science Fair time at Belleview High, and Josh is sure that this year, his is the project to beat.

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When Drake and Josh mistakenly assume that Walter's suspicious behavior means he is having an affair, they decide to take matters into their own hands, but ultimately end up cheating only themselves.

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Fueled by a love of the opposite sex and fear of commitment, Drake breaks up with his girlfriend only to realize that he may have made the wrong decision.

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When eye surgery leaves Helen temporarily blind and in Josh's care, Drake throws a private party in her apartment.

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After a botched weightlifting routine, Josh injures his foot and is forced into the hospital.

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An eight-year-old argument between Drake and Josh suddenly rekindles when their conflicting accounts of a incident at a San Diego Padres game finds them each placing the blame on the other.

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Drake's new girlfriend might be tougher than him. Josh trying to impress Mindy's parents might be even tougher.

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Megan möchte unbedingt ein Haustier haben und bestellt eins im Internet. Allerdings handelt es sich um ein ausgewachsenes Schaf. Mangels Stall stellt sie ‚Booob‘ in der Garage unter. Megan bietet ihren Brüdern an, dass sie sie drei Monate lang nicht mit Streichen behelligen wird – wenn sie sich dafür um die Schafsdame kümmern und das Tier obendrein vor ihren Eltern verstecken. Drake und Josh lassen sich auf das Angebot ein. Doch damit fangen die Schwierigkeiten erst an: Damit Audrey und Walter den ungebetenen Besucht nicht bemerken, muss Booob in Drakes und Joshs Zimmer übersiedeln. Dort angekommen, stellt sich heraus, dass das Schaf Nachwuchs erwartet, der auch nicht mehr lang auf sich warten lässt …

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Everyone turns it on Megan when they don't like Josh's teaching skills.

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Drake gets in trouble at school and is assigned to mentor a young boy.

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A TV producer casts Josh in crime-show re-enactments and is constantly mistaken for the real criminal.

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Drake and Josh are desperate to ride the awesome new roller-coaster, the Demonator, at their favorite amusement park, Mystic Mountain. However, their parents, who are going out for the night, force the boys to stay home and watch over their great-grandfather, who's recovering from surgery. After their parents leave, Drake issues the help of their geeky friends, Craig and Eric, to watch over the grandfather, while Drake, Josh, and Megan (who they agree to take after she threatens to tattle on them) jet off to ride the Demonator. However, nothing goes according to plan;...

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As payback for her meanness, Drake and Josh prank Megan into believing she's contacted outer space aliens.

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Drake and Josh go on the Dr. Phyllis Show and relive some of their most outlandish moments.

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